why would someone not lose weight on semaglutide does work without diet and exercise 7 Reasons You're Losing (& What To Do About It) Take control of your health – Not losing weight on semaglutide?

doi: 10.1016/j.physbeh.2018.01.025

Activation of GLP-1 receptors increases insulin secretion, decreases blood sugar and glucagon release, decreases gastric motility, and increases satiety [11-14]

Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility Carcinogenicity The dietary administration of fluoxetine to rats and mice for 2 years at doses of up to 10 and 12 mg/kg/day, respectively [approximately 1.2 and 0.7 times, respectively, the maximum recommended human dose (MRHD) of 80 mg on a mg/m2 basis], produced no evidence of carcinogenicity

If you are exploring medical options to manage your weight, you have likely heard of glucagon-like peptide-1 (GLP-1) receptor agonists